Extended Data Fig. 10: Boxplots of the relative abundance of selected taxa from LEfSe of Day 100 CR.
From: Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy
All data reported in this figure are based on 16S rRNA gene sequencing data from patients (n = 45). The relative abundance of Bacteroides, Bifidobacterium, Blautia, Faecalibacterium, Longicatena, and Ruminococcus are presented. Data is categorized by patients who did not achieve a Day 100 CR (No), and patients who achieved a Day 100 CR (Yes). Dots indicate relative abundance of the baseline fecal sample from a CAR T cell patient. Two-sided Wilcoxon rank-sum test was used to calculate the p-values, and the p-values were adjusted for multiple hypothesis testing. The middle line is the median, the box limits represent the upper and lower quartiles, the whiskers note 1.5x the interquartile range, and the dots represent the individual data points.
