Extended Data Fig. 1: Heatmaps of infection neutralization capacity against SARS-CoV-2 variants, anti-SARS-CoV-2 antibody responses, and antibody avidity in naive individuals and convalescents after BNT162b2 vaccination.
a,b, heatmaps of serum IC50 values for infection-neutralization capacity normalized to 107 viral RNA copies for serum infection-neutralization of SARS-CoV-2 variants (a) and IgG-type anti-spike S1 domain antibody titers (b) in 24 SARS-CoV-2 convalescents, 38 convalescents who did not receive vaccination #2, and 73 naive participants. c, heatmap of IgG-type anti-spike antibody avidity in 54 SARS-CoV-2 convalescents, 38 convalescents who did not receive the second vaccination, and 73 naive participants. For white areas within heatmaps data was not available. Abbreviations, pre – prior to first vaccination; #1 – first vaccination time point; 2 – second vaccination; #3 – third vaccination; w2 – two weeks after respective vaccination; m4 – 4 months after vaccination; m7 – 7 months after vaccination; inf. m5 – 5 months after SARS-CoV-2 infection; inf. m8 – 8 months after SARS-CoV-2 infection; BAU – binding antibody units.
