Extended Data Fig. 10: Specimens evaluated for the presence of Omicron by VIP.

a, Heatmap colored by the percent of available variant genomes on GISAID with a particular variant mutation broken down by variant lineage. b, Delta and Omicron case counts and proportion of Omicron by mCARMEN VIP from specimens collected at the Harvard University CLIA Laboratory (HUCL) from December 6-16 2021, related to Fig. 6b (n = 430). Green: Omicron; Black: Delta. c, Delta and Omicron case counts between VIP and NGS results with the proportion of Omicron by VIP below (n = 1,557). Specimens collected at the Broad Institute from the state of Massachusetts. Blue: Omicron; Black: Delta. d, Scatter plot of the proportion of Delta based on the VIP and NGS variant lineage results from c and Fig. 6c. Linear regression line fit shown as black line; R2 = 0.998. e, Time delay from specimen collection to variant lineage result between VIP and NGS. Data represents the proportion of Omicron from specimens collected at HUCL and within the state of Massachusetts. Blue closed circles: VIP MA specimens from c; Blue open circles: NGS MA specimens from c; Green: VIP HUCL specimens from b.