Extended Data Fig. 8: Difference in standardized, adjusted PRS between WGS and imputed genotyping arrays for 22 individual samples.
From: Development of a clinical polygenic risk score assay and reporting workflow
The PRSstd-adj of 22 samples obtained from WGS and from imputed genotyping arrays are subtracted, and the distribution of the difference of the scores is plotted for each disease. Abbreviations: AFib, atrial fibrillation; BrCa, breast cancer; CAD, coronary artery disease; CRCa, colorectal cancer; IMPU, imputed genotype data; MGBB, Mass General Brigham Biobank; PrCa, prostate cancer; PRS, polygenic risk score; T2D, type 2 diabetes; WGS, whole genome sequencing.
