Extended Data Fig. 1: Quantitative infectious viral loads versus overall virus isolation success. | Nature Medicine

Extended Data Fig. 1: Quantitative infectious viral loads versus overall virus isolation success.

From: Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2

Extended Data Fig. 1

(a) Vero E6 (Pre-VOC and Delta) or Vero E6-TMPRSS (Omicron BA.1) cells were inoculated with 10-fold serial dilutions of nasopharyngeal swabs collected from SARS-CoV-2 infected individuals. Plates were fixed 27 h post-infection and following the staining with SARS-CoV-2 specific antibodies, the number of focus forming units (FFU)/mL was calculated for each sample. Error bars indicate mean ± SD. p-values were calculated using one-way ANOVA. ***: p < 0.0003; ****p < 0.0001. (b) The total number of positive and negative samples defined by titration and virus isolation for each patient group. Patients with detectable foci-forming units were assigned to the (+) group while patients without detectable focus-forming units were assigned to the (-) group). Cohens kappa agreement is shown.

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