Table 5 Mendelian randomization IVW estimates for the effect of genetic liability to IBD, Crohn’s, and UC on autism and vice versa
From: Parental inflammatory bowel disease and autism in children
Exposure | Outcome | OR (95% CIs) | P |
|---|---|---|---|
Genetic liability to IBD | Autism | 1.02 (1.0, 1.05) | 0.1 |
Genetic liability to UC | Autism | 1.04 (1.01, 1.07) | 0.006 |
Genetic liability to Crohn’s | Autism | 1.01 (1.0, 1.04) | 0.2 |
Genetic liability to autism | IBD | 0.90 (0.73, 1.11) | 0.32 |
Genetic liability to autism | UC | 0.95 (0.77, 1.18) | 0.65 |
Genetic liability to autism | Crohn’s | 0.85 (0.63, 1.15) | 0.29 |
