Extended Data Fig. 1: Model structure flow diagram with transition rates between states.

a, Overview of extended SEIR transmission model. b, Diagram of hospitalization provided symptomatic infections. c, Diagram of antiviral therapies provided symptomatic infections. d, Diagram of vaccination and waning immunity. Note that the complex infection dynamic as shown in a has been encapsulated within a single pink box. All states and parameters are defined in Supplementary Tables 3 and 4.