Extended Data Fig. 5: Genotyping analysis of patient single CD34+ cell expansions. | Nature Medicine

Extended Data Fig. 5: Genotyping analysis of patient single CD34+ cell expansions.

From: CRISPR–Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia

Extended Data Fig. 5

CD34 + cells were sorted by MACS from bone marrow cells of patients 9 months after transplantation, and their single-cell expansions were analyzed for genotype by sanger sequencing. It was found that 88.3% (n=77) and 79.8% (n=104) of the CD34+ cells of the two patients were biallelic editing.

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