Fig. 1: Normal tissue biodistribution of 89ZED88082A.
From: Whole-body CD8+ T cell visualization before and during cancer immunotherapy: a phase 1/2 trial
a, Representative 89ZED88082A PET scan maximum intensity projection day 2. A whole-body visualization is available as Supplementary Video. b–e, Axial views of the same scan fused with low-dose CT. Arrows indicate uptake in Waldeyer’s ring, cervical lymph nodes (b), spleen, bone marrow (c), renal cortex, small intestine (d) and inguinal lymph nodes (e). f,g Pretreatment uptake with 95% confidence bands across tissues adjusted for protein dose, projected at 10 mg dose (n = 9), days 0 (1 h), 2, 4 and 7 (±1 day), with mean SUVmean (f) and mean SUVmax (g) for lymph nodes and tonsils, not visible on day 0.
