Extended Data Fig. 1: Biodistribution of 89ZED88082A in normal tissues.
From: Whole-body CD8+ T cell visualization before and during cancer immunotherapy: a phase 1/2 trial
a, Biodistribution per protein dose cohort pretreatment. Graphs show the average SUVmean with 95% confidence bands of 89ZED88082A in the blood pool and normal tissues at days 0 (1 h), 2, 4, and 7. Colours reflect the dose cohorts with 4 mg in blue (n = 3) and 10 mg in red (n = 6). Note the different scales of the y-axis. b, Table showing average changes in tracer uptake values between pre- and ontreatment PET scans, projected at 4 weeks. Pinteraction is shown for the correlation between change and best overall response (PD vs. SD/PR/CR). ND = not determined.
