Table 2 Overview of diagnostic panel sera assessed for the presence of VACV-reactive or MPXV-reactive antibodies by ELISA and MVA-neutralizing or MPXV-neutralizing antibodies by PRNT

From: Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals

 

Before 1974 and PCR

Before 1974 and PCR+

After 1974 and PCR

After 1974 and PCR+

VACV ELISA

 Sera

19

13

21

19

 Responder

10

10

0

5

 Percentage (%)

53

77

0

26

 GMT

43

846

10

24

MPXV ELISA

 Sera

11

12

5

7

 Responder

1

8

0

0

 Percentage (%)

9

67

0

0

 GMT

10

123

10

10

MVA PRNT

 Sera

11

12

5

7

 Responder

0

5

0

0

 Percentage (%)

0

42

0

0

 GMT

10

41

10

10

MPXV PRNT

 Sera

11

12

5

7

 Responder

7

10

0

5

 Percentage (%)

64

83

0

71

 GMT

41

185

10

176

Total

 Sex (M/F)a

14/5

12/1

17/4

19/0

 Age (years)b

57 (range, 51–80)

57 (range, 52–65)

29 (range, 20–42)

35 (range, 21–41)

  1. aNumber of assessed serum samples per group from males (M) versus females (F).
  2. bThe median age per group, including the upper and lower limit, is given.