Extended Data Fig. 8: Drug-induced effects on gene expression in AML blasts. | Nature Medicine

Extended Data Fig. 8: Drug-induced effects on gene expression in AML blasts.

From: Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials

Extended Data Fig. 8

a, Gene Ontology enrichment analysis on RNA-sequencing (RNA-seq) results from AML blasts collected from Patients 16, 17, and 19 of AML Cohort 4 at several pre- and post-dose timepoints across Cycle 1. b, Pathway analysis ranking deregulated biological pathways upon IACS-010759 treatment from patients described in (a).

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