Fig. 1: Overview of enrollment into the different dose levels and phases of the study. | Nature Medicine

Fig. 1: Overview of enrollment into the different dose levels and phases of the study.

From: Concurrent intrathecal and intravenous nivolumab in leptomeningeal disease: phase 1 trial interim results

Fig. 1

The study consisted of two parts: a phase 1 dose escalation portion and a phase 1b dose expansion cohost at the recommended dose. This graph details the patients enrolled on each dose level (5, 10, 20 and 50 mg after protocol amendment) and phase (dose escalation and dose expansions) of the clinical trial. A total of 25 patients were treated.

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