Extended Data Fig. 7: Exhaustion panel expression and flow-based immunophenotyping.
From: Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
(a) Trajectory scatter plots show the percent of T cells expression for LAG3, PDCD1, and TIM3 across time for flow-based immunophenotyping (left) and single-cell RNA sequencing (scRNA-seq) data. Ribbons refer to the 95% confidence level interval for predictions using a ‘loess’ model to fit the line. (b) Trajectory scatter plots show the percent of T cells expression for the combination of LAG3, PDCD1, and TIM3 across time for flow-based immunophenotyping. Ribbons refer to the 95% confidence level interval for predictions using a ‘loess’ model to fit the line.
