Fig. 4: CAR-T cell immunophenotyping.
From: Transcriptional signatures associated with persisting CD19 CAR-T cells in children with leukemia
Bar plots show custom gene modules that functionally characterize CAR-T cells. The height of the bar refers to the fraction of cells per cell type that express the gene. Higher bars indicate that more cells of that cell type are expressing that gene. The shading refers to the average scaled expression of those genes for that cell type. Darker shading indicates that the expression of that gene is above the average expression of that gene across all cell types. All CAR-T cells (product, early, mid and late) from all patients (n = 10) are analyzed. DN, double-negative; TCM, central memory; TEM, effector memory.
