Extended Data Fig. 2: Trial-level analyses for the association between treatment effects on GFR slope and treatment effects on the clinical endpoint.
From: A meta-analysis of GFR slope as a surrogate endpoint for kidney failure
Circles represent separate studies. Sizes are proportional to the number of events (kidney failure with replacement therapy, GFR <15 mL/min/1.73m2, or doubling of serum creatinine). Colors indicate intervention type. The black line is the line of regression through the studies. Blue lines show the 95% pointwise Bayesian prediction bands computed from the model. Red triangles indicate studies where the estimated treatment effects are beyond the margins.
