Fig. 2: Stool butyrate over time in recipients of allogeneic HCT.
a, Intention-to-treat analysis of stool butyrate levels in mmol kg−1 (y axis) as measured through allogeneic HCT where time (x axis) in days relative to allogeneic HCT is shown. Yellow dots with a black outline represent butyrate levels at time points when participants were consuming RPS; yellow dots with no outline represent butyrate levels at time points when participants were not taking RPS. b, Per protocol analysis of stool butyrate levels in mmol kg−1 (y axis) when participants were on RPS versus when they were not (x axis). A mixed random effects model was used to adjust for repeated measures from the same individuals. The median values for the no RPS and the yes RPS groups are 3.06 mmol kg−1 and 10.76 mmol kg−1, respectively. ****P value from the mixed random effects model coefficient for RPS versus stool butyrate level was 2 × 10−13.
