Extended Data Fig. 3: SteatoSITE RNA-seq according to NAS scores. | Nature Medicine

Extended Data Fig. 3: SteatoSITE RNA-seq according to NAS scores.

From: An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease

Extended Data Fig. 3

a, UpSet plot of differentially assessed genes (DEGs), showing DEGs belonging to individual sets (according to NAFLD activity score (NAS) ≤ 2, NAS 3/4 and NAS ≥ 5) and the intersection of DEGs across all NAS sets. Set sizes are presented as bars and their composition is described by the bottom panel. b, Top 10 molecular functions (gene ontology (GO) terms) identified with one-sided gene set enrichment analysis based on the differentially expressed genes of NAS ≤ 2; c, NAS 3/4; d, NAS ≥ 5 (Benjamin and Hochberg false discovery rate q < 0.05 and fold-change of ≥1).

Back to article page