Extended Data Fig. 4: Transcriptomic analysis of CD4 + T cells from NSV and ART-suppressed participants (Supplementary to Fig. 4). | Nature Medicine

Extended Data Fig. 4: Transcriptomic analysis of CD4 + T cells from NSV and ART-suppressed participants (Supplementary to Fig. 4).

From: Viral and host mediators of non-suppressible HIV-1 viremia

Extended Data Fig. 4

(a) Gene Set Enrichment Analysis (GSEA) plots show selected pathways that were up- or down-regulated in NSV vs. ART-suppressed (control) groups. Adjustments were made for multiple comparisons using the Benjamini-Hochberg method. (b) Two-sided Wilcoxon rank sum test was used to evaluate interferon (IFN)-related gene expression levels between NSV and control groups. Bars represent median values. (c) Gene network related to IFN signaling enriched in the control group generated by STRING analysis.

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