Table 5 Results of sensitivity analyses

From: Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

 

All hematological malignancies

Lymphoid malignancies

Myeloid malignancies and AL

#

ERR/100 mGy

95% CI

#

ERR/100 mGy

95% CI

#

ERR/100 mGy

95% CI

Main results

790

1.96

1.10

3.12

578

2.01

1.02

3.42

203

2.02

0.47

4.77

 ABM doses

            

 Doses lagged by 1 year

790

1.99

1.13

3.16

578

2.04

1.05

3.47

203

2.07

0.54

4.80

 Doses lagged by 5 years

790

1.06

0.45

1.82

578

1.25

0.53

2.20

203

0.60

−0.43

2.20

 Use of median of dose realizations instead of mean

790

2.08

1.09

3.42

578

2.13

0.99

3.75

203

2.17

0.36

5.35

 Analyses restricted to individuals with cumulative doses up to:

 99th percentile

777

3.17

1.90

4.91

567

3.02

1.59

5.09

201

3.81

1.43

8.20

 98th percentile

761

3.54

2.08

5.55

554

3.27

1.66

5.63

198

4.43

1.67

9.62

 95th percentile

710

2.80

1.27

4.94

520

2.79

1.02

5.41

181

2.88

0.34

7.75

Exclusions

 5 years from first CT

524

2.36

1.21

4.05

381

2.54

1.19

4.66

139

1.74

0.05

5.25

 10 years from first CT

261

2.67

1.02

5.69

185

3.12

1.13

7.08

72

1.28

-0.62

8.11

 Individuals born before the start of cancer registration

490

1.54

0.68

2.80

365

1.59

0.60

3.14

119

1.84

0.20

5.29

 Hospitals with low reporting consistency

603

1.93

0.97

3.29

440

2.17

1.00

3.93

158

1.49

0.00

4.31

 Follow-up 2 years after country-specific maximum age at exposure

491

1.27

0.49

2.39

356

1.26

0.39

2.63

128

1.61

0.11

6.61

 Individuals with no vital status

739

1.73

0.89

2.97

541

1.91

0.91

3.35

189

1.39

0.03

3.85

United Kingdom—main results

 

NA

  

276

2.77

1.12

5.55

 

NA

  

 Excluding individuals who underwent transplant

 

NA

  

256

2.57

0.97

5.31

 

NA

  
  1. #, number of hematological malignancies cases; NA, not applicable.