Extended Data Fig. 3: Kaplan-Meier estimates of overall survival with p-values calculated using a stratified log-rank test.

Numbers of patients at risk at different time points are indicated below the survival curves. Points and error bars on the embedded forest plots indicate hazard ratios (HR) with 95% confidence intervals (CI), correspondingly. HR, CI and p-values are calculated from cox proportional hazards models corrected by cancer stage. Patients are stratified by mutational status of genes indicated for testing in NGTDC across all cancer types (n = 11337). Exact p-values can be found in Supplementary Table S2.