Extended Data Fig. 4: Additional Outcome Analysis. | Nature Medicine

Extended Data Fig. 4: Additional Outcome Analysis.

From: Feasibility of functional precision medicine for guiding treatment of relapsed or refractory pediatric cancers

Extended Data Fig. 4

(a) Overall response distributions of therapeutic response prior to study enrollment in TPC cohort and FPM-guided patients. P values from two-sided Barnard’s test comparing ORR. (b) Kaplan-Meier survival curves of previous regimen PFS in TPC and FPM-guided patients. P values from Logrank test analysis of PFS data. (c) OR distributions of previous versus current regimen in TPC cohort. P values from two-sided McNemar’s Paired test comparing ORR. (d) Kaplan-Meier survival curves of the previous versus current regimen PFS in TPC cohort. P values from two-sided Cox Proportional Hazard test analysis of paired PFS data. PR = Previous Regimen, TPC = Treatment of Physician’s Choice, FPM = FPM-guided.

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