Table 1 Baseline characteristics before and after weighting with propensity scores

From: Sustained effect of prasinezumab on Parkinson’s disease motor progression in the open-label extension of the PASADENA trial

Characteristic

Before weighting

After weighting

PASADENA, n = 271

EC PPMI, n = 303

SMD

PASADENA, n = 271

EC PPMI, n = 270

SMD

Age (years), mean (s.d.)

59.98 (9.00)

62.11 (8.53)

0.243

59.98 (9.00)

61.20 (9.28)

0.133

Male sex, n (%)

188 (69.4)

202 (66.7)

0.058

188.0 (69.4)

189.3 (70.1)

0.017

MDS–UPDRS Part III, mean (s.d.)

21.15 (8.96)

21.17 (8.85)

0.003

21.15 (8.96)

21.13 (9.71)

0.001

H&Y 2, n (%)

201 (74.2)

183 (60.4)

0.297

201.0 (74.2)

205.7 (76.2)

0.047

PD diagnosis (months), mean (s.d.)

9.89 (6.34)

4.87 (5.36)

0.855

9.89 (6.34)

9.20 (5.61)

0.115

Years of education ≥12, n (%)

244 (90.0)

279 (92.1)

0.072

244.0 (90.0)

236.2 (87.5)

0.080

Montreal Cognitive Assessment, mean (s.d.)

28.17 (1.79)

27.23 (2.26)

0.462

28.17 (1.79)

28.02 (1.89)

0.082

DaT–SPECT putamen bilateral, mean (s.d.)

0.92 (0.26)

0.81 (0.28)

0.436

0.92 (0.26)

0.92 (0.31)

0.018

  1. Note: SMD ≤ 0.2 indicates balance between groups. EC, external control.