Table 1 Baseline characteristics before and after weighting with propensity scores
Characteristic | Before weighting | After weighting | ||||
---|---|---|---|---|---|---|
PASADENA, n = 271 | EC PPMI, n = 303 | SMD | PASADENA, n = 271 | EC PPMI, n = 270 | SMD | |
Age (years), mean (s.d.) | 59.98 (9.00) | 62.11 (8.53) | 0.243 | 59.98 (9.00) | 61.20 (9.28) | 0.133 |
Male sex, n (%) | 188 (69.4) | 202 (66.7) | 0.058 | 188.0 (69.4) | 189.3 (70.1) | 0.017 |
MDS–UPDRS Part III, mean (s.d.) | 21.15 (8.96) | 21.17 (8.85) | 0.003 | 21.15 (8.96) | 21.13 (9.71) | 0.001 |
H&Y 2, n (%) | 201 (74.2) | 183 (60.4) | 0.297 | 201.0 (74.2) | 205.7 (76.2) | 0.047 |
PD diagnosis (months), mean (s.d.) | 9.89 (6.34) | 4.87 (5.36) | 0.855 | 9.89 (6.34) | 9.20 (5.61) | 0.115 |
Years of education ≥12, n (%) | 244 (90.0) | 279 (92.1) | 0.072 | 244.0 (90.0) | 236.2 (87.5) | 0.080 |
Montreal Cognitive Assessment, mean (s.d.) | 28.17 (1.79) | 27.23 (2.26) | 0.462 | 28.17 (1.79) | 28.02 (1.89) | 0.082 |
DaT–SPECT putamen bilateral, mean (s.d.) | 0.92 (0.26) | 0.81 (0.28) | 0.436 | 0.92 (0.26) | 0.92 (0.31) | 0.018 |