Extended Data Fig. 7: Correlation plots between the tetracycline antimicrobial resistance genes (ARGs) detected in the bacterial microbiome and the 50 most abundant bacterial genera detected in the doxy-PEP DNA-seq samples at (a) day-0 and (b) month-6. | Nature Medicine

Extended Data Fig. 7: Correlation plots between the tetracycline antimicrobial resistance genes (ARGs) detected in the bacterial microbiome and the 50 most abundant bacterial genera detected in the doxy-PEP DNA-seq samples at (a) day-0 and (b) month-6.

From: Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Extended Data Fig. 7

Day-0: n = 58; month-6: n = 69. Color and size of the points represent the strength of correlation between the tetracycline ARG abundance and the bacterial genera abundance as calculated with the two-sided Spearman’s correlation test. Correlations with significant p-values, adjusted for multiple comparisons, are denoted with asterisks (p < 0.05*, p < 0.01**). Tetracycline ARGs with an empty row represented cases where there was not enough data to evaluate for correlation.

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