Extended Data Fig. 3: Impact of Doxy-PEP use on abundance of tetracycline and non-tetracycline antimicrobial resistance genes (ARGs) for DNA-seq samples and RNA-seq samples. | Nature Medicine

Extended Data Fig. 3: Impact of Doxy-PEP use on abundance of tetracycline and non-tetracycline antimicrobial resistance genes (ARGs) for DNA-seq samples and RNA-seq samples.

From: Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Extended Data Fig. 3

ARG class abundance over time within the doxy-PEP arm for (a) DNA-seq samples (n = 80) and (b) RNA-seq samples (n = 55). P-values were calculated using the two-sided Wilcoxon rank-sum test and adjusted for multiple comparisons. Boxplot elements include a center line (median), box limits (upper and lower quartiles), whiskers (1.5x interquartile range). Significant p-values (<0.05) are bolded. Abbreviations: Padj, adjusted p-value.

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