Fig. 2: Characteristics of concordant and discordant profiles.
From: Subclassification of obesity for precision prediction of cardiometabolic diseases
Discordant profiles discovered in the UKB and robustly replicated across three independent cohorts. a, UMAP 2D projection. Colors denote profile allocations. b, Cluster weights. c, Forest plot of average biomarker residuals characterizing each profile. Points and error bars represent estimates and 95% confidence intervals of average residual values of each biomarker. The dashed line represents a residual of 0. Female sample sizes: UKB = 77,207; TMS = 1,542; RS = 5,704; GHS = 7,301. Male sample sizes: UKB = 67,904; TMS = 1,633; RS = 4,289; GHS = 7,353. DBP, diastolic blood pressure; SBP, systolic blood pressure; SCR, serum creatinine; WHR, waist-to-hip ratio.
