Extended Data Fig. 1: CHMI dose and time-to-parasitaemia.

A. Number of infected blood fed mosquitoes per participant at the controlled human malaria infection (CHMI). A black horizontal line represents the median. B. Development of parasitaemia per day after CHMI. Lines with different symbols represent different participants. The horizontal dotted grey line represents the cut-off for parasitaemia (100 parasites/mL blood) at which treatment is given. The horizontal continuous grey line represents the lowest limit of detection of the assay (50 parasites/mL blood).