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Using a sex- and gender-informed lens to enhance care in Parkinson’s disease

Sex and gender differences in Parkinson’s disease should be a priority for researchers and clinicians, to ensure appropriate care is provided to patients.

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Fig. 1: Recommendations to improve the patient journey in PD.

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Acknowledgements

The inspiration for this Comment came from the Women’s Brain Foundation Parkinson's Disease Roundtable held in 2023, sponsored by AbbVie; the authors thank all sponsors, participants, mentors and organizers. The manuscript received no specific grants or funds from AbbVie or any funding agency in the public, commercial, or not-for-profit sectors.

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Correspondence to Laura Castro-Aldrete or Antonella Santuccione-Chadha.

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L.C.-A. is the scientific project manager of the Women's Brain Foundation. A.S.C. is the co-founder and pro bono CEO of the Women's Brain Foundation. E.V.: the views expressed are those of the author and not of the Innovative Health Initiative Joint Undertaking or its founding members. A.O. and R.F. contributed as people with lived experience. All other authors declare no competing interests.

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Castro-Aldrete, L., Huc, M., Domingos, J. et al. Using a sex- and gender-informed lens to enhance care in Parkinson’s disease. Nat Med 31, 367–369 (2025). https://doi.org/10.1038/s41591-024-03363-2

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