Extended Data Fig. 5: Capillary EC characterisation.

a, Quantification of fatty acid related gene markers across arterial (art_ec, GJA5+/VWF+), capillary (cap_ec, RGCC+/VWF+) and venous (ven_ec, ACKR1+/VWF+) EC using multiplexed-smFISH. n = 8 sections, 1 donor. Statistical analysis was performed using the Wilcoxon Rank Sum Test with Benjamini-Hochberg adjustment. ns = not significant. ** = adjusted p value <0.01. *** = adjusted p value < 0.001. **** = adjusted p value < 0.0001. For box plots in a, the centre line shows the median, the box limits represent the 25th and 75th percentiles, the whiskers show the minimum and maximum values, and the dots represent potential outliers. b, Dotplot shows expression of FOXF1 downstream targets genes across lung EC populations. Fraction of expressing cells and average expression within each cell type is indicated by dot size and colour, respectively. c & d, H&E staining and cell2location predicted cell abundance (5% percentile) of uterine vascular cell states (uterine_pc, uterine_smc, and endometrium_cap_ec) in the endometrium and myometrium location of the uterus in the (c) proliferative state, and (d) secretory state. Scale bars = 1 mm.