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Seven unanswered questions about blockbuster weight-loss drugs

Nature Medicine volume 30, pages 3389–3391 (2024)Cite this article

Nature Medicine asks experts to explain the research priorities for the field of GLP-1 receptor agonists such as semaglutide, from sex differences to how they might treat addiction.

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Fig. 1: Cumbersome and expensive.

References

  1. Yeo, Y. H. et al. Ann. Intern. Med. 177, 1289–1291 (2024).

    Article  PubMed  Google Scholar 

  2. Lincoff, A. M. et al. N. Engl. J. Med. 389, 2221–2232 (2023).

    Article  CAS  PubMed  Google Scholar 

  3. Jager, K. J. et al. Kidney Int 96, 1048–1050 (2019).

    Article  PubMed  Google Scholar 

  4. Perkovic, V. et al. N. Eng. J. Med. 391, 109–121 (2024).

    Article  CAS  Google Scholar 

  5. Wang, W. et al. Ann. Intern. Med. 177, 1016–1027 (2024).

    Article  PubMed  Google Scholar 

  6. üthi, H. et al. eClinicalMedicine 68, 102429 (2024).

    Article  Google Scholar 

  7. Quddos, F. et al. Sci. Rep. 13, 20998 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Celis-Morales, C. A. et al. Diabetes Care 45, 634–641 (2022).

    Article  CAS  PubMed  Google Scholar 

  9. Montero, A., Sparks, G., Presiado, M. & Liz Hamel, L. KFF https://go.nature.com/48FgF43 (10 May 2024).

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    Mike May

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May, M. Seven unanswered questions about blockbuster weight-loss drugs. Nat Med 30, 3389–3391 (2024). https://doi.org/10.1038/s41591-024-03380-1

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