Extended Data Fig. 3: Crude interaction analysis between change in weight and effect of the intervention on the primary outcome.

Data are presented as means with shaded areas representing 95% confidence intervals at 3 months with n = 216 (A) and 6 months with n = 212 (B). Estimates and p-values (two-tailed, linear regression) are given per 10 kg change in weight change, and no adjustments are made for multiple comparisons.