Extended Data Fig. 4: Metastatic potential as a function of different CTC cluster sizes.

(a) Schematic illustration of the experimental design. (b) Representative images of bioluminescent signals in mice within specified experimental groups. (c) Plot showing normalized bioluminescent signal across experimental groups (minimum n = 4 per group, where points represent individual mice) three weeks after tumor cell injection. P = 0.0089 by two-sided Mann-Whitney test. The cross bar represents the mean. Panel (a) was created with BioRender (https://biorender.com).