Extended Data Fig. 1: Cutaneous infiltration of clonal CD30+ T cells. | Nature Medicine

Extended Data Fig. 1: Cutaneous infiltration of clonal CD30+ T cells.

From: Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody

Extended Data Fig. 1

Immunohistochemical analysis (n=1) of a skin biopsy obtained from the left dorsal region of the patient at nine months post CAT-T therapy. The panels display staining for H&E, CD3, CD5, CD4, Granzyme B, MUM1, and CD30, with the magnification indicated in each image. The biopsy revealed dense lymphocytic infiltrations associated with smaller blood vessels. These infiltrates were positive for CD3, MUM1, Granzyme B, and CD30, predominantly negative for CD4, and exhibited partial loss of CD5.

Back to article page