Extended Data Fig. 4: Duodenal infiltration of clonal T cells.

Immunohistochemical analysis (n=1) of a duodenal biopsy performed at twelve months post CAR-T infusion. The panels display staining for H&E, CD3, CD5, CD4, Granzyme B, MUM1, and CD30, with the magnification indicated in each image. The biopsy revealed again dense lymphocytic infiltrations. These infiltrates were positive for CD3, CD5, and Granzyme B, partially positive for CD4, and negative for MUM1 and CD30.