Extended Data Fig. 7: Putative and Reconstructed Genome capture by time.
From: Gut microbiome evolution from infancy to 8 years of age
(A) Putative Genome count per sample increases until approximately 3 YOL before stabilizing (n = 177 stools from 20 infants). (B) Timepoints 5 and 6, covering the 3 YOL and 7-8 YOL infant samples, harbor more Putative Genomes than the early-life timepoints, taken within the first 2 YOL (n = 16 infants, 6 stools per infant). (C) Putative Genome count per timepoint is stable longitudinally (n = 10 mothers 3-4 stools per mother). (D) Comparison of Putative Genome counts per individual before and after quality filtering (n = 10 mothers, 20 infants). (E) Number of quality-filtered Putative Genomes per dRep secondary cluster during MAG dereplication. (F) Comparison of MAG counts for each sample before and after dereplication. For (A) and (F), measures of center are a smoothed conditional mean (LOESS local polynomial regression), with 95% CI shown in gray. For (B) and (C), boxes represent IQR with median line, and whiskers extend to 1.5xIQR.
