Extended Data Fig. 2: Broad rim lesions (BRL) with and without iron rims. | Nature Medicine

Extended Data Fig. 2: Broad rim lesions (BRL) with and without iron rims.

From: Broad rim lesions are a new pathological and imaging biomarker for rapid disease progression in multiple sclerosis

Extended Data Fig. 2

The left panel displays a BRL lesion without an iron rim, whereas the right panel displays a BRL lesion with an iron rim. a and b, Two broad rim lesions stained for HLA-DR. c and d, Inserts in a and b are shown in higher magnification in c and d. e and f, Turnbull staining reveals a high number of iron containing myeloid cells at the border of the lesion in f, but not in e. Scale bars in a 2,5 mm, in b 5 mm, and in c to f 250 µm.

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