Extended Data Fig. 2: Cost analysis of technology nodes and node combinations used in the TuPro project per cohort.

a, adjuvant, b, palliative SOC cohort, c, palliative beyond SOC. The x-axis shows the marginal costs in Swiss francs (CHF) of production, representing the cost of one additional analysis using a combination of technology nodes running at full capacity. The y-axis shows the number of patients that would have all relevant information available with the corresponding subset of technologies when compared to using all technologies. The labels on each data node indicate the individual technology nodes and combined cost per sample. Each dot corresponds to a different combination of technologies associated with a total cost for that combination. Only the best combinations are shown, as other combinations have a higher cost or a smaller number of samples with available relevant information. This analysis provides a better understanding of the cost-effectiveness of various diagnostic approaches and the trade-offs between the generated information and associated expenses.