Fig. 1: Trial participant randomization and follow-up scheme.
Of 128 patients screened for inclusion, 71 were randomized to receive 30 mg rentosertib QD (n = 18), 30 mg rentosertib BID (n = 18), 60 mg rentosertib QD (n = 18), or placebo (n = 17) over the course of 12 weeks. Sixteen patients discontinued treatment prior to the end of treatment.
