Extended Data Fig. 8: Correlation analysis of protein abundance of genes previously associated with aging-related dysfunction. | Nature Medicine

Extended Data Fig. 8: Correlation analysis of protein abundance of genes previously associated with aging-related dysfunction.

From: A generative AI-discovered TNIK inhibitor for idiopathic pulmonary fibrosis: a randomized phase 2a trial

Extended Data Fig. 8

Correlation analysis of protein abundance of genes (IL10, CD5, COL6A3) previously associated with aging-related dysfunction, such as immunity and ECM remodeling, with change in FVC from week 0 to week 12 and time on treatment. Left panel: n = 43 patient at each visit; P values calculated by two-sided Pearson correlation analysis; Right panel: n = 11 patients in placebo, n = 11 patients in 30 QD; n = 11 patients in 30 BID, n = 10 patients in 60 QD, boxes and whiskers are quartiles; P values calculated by paired t-test.

Back to article page