Extended Data Fig. 3: Association between intratumoral apMCs and patient survival. | Nature Medicine

Extended Data Fig. 3: Association between intratumoral apMCs and patient survival.

From: Mobilizing antigen-presenting mast cells in anti-PD-1-refractory triple-negative breast cancer: a phase 2 trial

Extended Data Fig. 3

(a) Kaplan-Meier analyses of apMC status (median as cutoff) with PFS (left panel) and OS (right panel) for metastatic TNBC. A total of 197 patients were included and one patient without available PFS/OS data was not included in this analysis. (b) Multivariate cox analyses of apMCs concerning PFS and OS in metastatic TNBC. (c) Kaplan-Meier analyses of apMC status (median as cutoff) with DFS (left panel) and OS (right panel) for primary TNBC. A total of 360 patients were included (with RNA-seq, and n = 186 with tissue sections for staining) and all patients had available OS data. Four patients without available DFS data were not included in the DFS analysis. (d) Multivariate cox analyses of apMCs concerning DFS and OS in primary TNBC. Two-sided log-rank test (a, c) and multivariate Cox regression model (b, d).

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