Extended Data Fig. 9: Principal component analysis (PCA) of proteomic data before and after z-score based normalization. | Nature Medicine

Extended Data Fig. 9: Principal component analysis (PCA) of proteomic data before and after z-score based normalization.

From: Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases

Extended Data Fig. 9

a, The PCA plot of ethylenediaminetetraacetic acid (EDTA) plasma samples from each contributor in GNPC version 1. The red dots represent first two proteomic principal components (PCs) of samples from an individual contributor against the grey dot representing proteomic PCs of all sample from every contributor. b, The PCA plot of sodium citrate plasma samples from a single contributor ‘K’. c-d, The PCA plots of z-score normalized proteomic data from the c, EDTA and d, Citrate samples across all contributors.

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