Extended Data Fig. 10: Electrophysiology of neurons in response to safusidenib treatment.
From: Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial
Example whole-cell patch clamp recordings from each pyramidal neuron recorded within tissue samples obtained from patients pre- (top; n = 11 neurons) and post- (bottom; n = 14 neurons) treatment with the mIDH inhibitor. All voltage responses are in response to a 230 pA current step injection. Scale bar, 20 mV, 200 ms.
