Extended Data Table 4 Available targeted treatments and pathways

From: Genomically matched therapy in advanced solid tumors: the randomized phase 2 ROME trial

  1. Overview of available targeted treatments and their associated pathways.
  2. * Drugs included in the V4 protocol amendment in October 2022.
  3. ** hTMB defined as ≥10 mutations per megabase in solid and/or liquid NGS.