Fig. 1: Distribution and independence of pfhrp2/3 deletions in Africa among surveys of symptomatic individuals collated from the WHO Malaria Threat Maps database. | Nature Medicine

Fig. 1: Distribution and independence of pfhrp2/3 deletions in Africa among surveys of symptomatic individuals collated from the WHO Malaria Threat Maps database.

From: Global risk of selection and spread of Plasmodium falciparum histidine-rich protein 2 and 3 gene deletions

Fig. 1

a, Percentage of pfhrp2-deleted samples together with pfhrp3 deletions. The mean and 95% CI are shown with points and ranges, with the vertical dashed line indicating the continent-wide estimate based on a beta-binomial model. The sample size per country is: Burkina Faso (32), Cameroon (49), DRC (3), Djibouti (272), Eritrea (198), Ethiopia (195), Gabon (2), Ghana (37), Equatorial Guinea (92), Kenya (29), Madagascar (1), Mozambique (201), Nigeria (18), Senegal (3), Sierra Leone (2), South Sudan (85), Chad (10), Togo (1), Tanzania (25), Uganda (73) and Zambia (12). b, Relationship between the percentage of pfhrp2-deleted samples with pfhrp3 deletions and malaria slide prevalence in 2–10 year olds based on the Malaria Atlas Project estimates. c, Relationship between the percentage of samples with pfhrp3 deletions and malaria prevalence. In all plots, the point size represents the number of samples from each survey used to derive estimates. In b and c, an overdispersed binomial regression model fit (blue) shows the mean relationship, with the 95% CI of the regression fit shown with shaded bands. Data is the from WHO Malaria Threat Maps database3.

Back to article page