Extended Data Fig. 4: Pharmacodynamics Heat Map for Serum Factors in Patients with Melanoma treated with Adjuvant Nivolumab plus Relatlimab versus Nivolumab Alone in RELATIVITY-098. | Nature Medicine

Extended Data Fig. 4: Pharmacodynamics Heat Map for Serum Factors in Patients with Melanoma treated with Adjuvant Nivolumab plus Relatlimab versus Nivolumab Alone in RELATIVITY-098.

From: Adjuvant nivolumab and relatlimab in stage III/IV melanoma: the randomized phase 3 RELATIVITY-098 trial

Extended Data Fig. 4

The figure presents a heatmap summarizing linear mixed effect models for a cytokine panel separated by treatment arm. Each individual box represents the statistical comparison between the on-treatment time point on the x-axis with the baseline time point, colored by the difference in means, in which blue is lower on treatment and red is higher on-treatment. C, cycle; D, day; ns, not significant/P > 0.1. •P ≤ 0.1(trending), *P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, and ****P ≤ 0.0001.

Back to article page