Supplementary Figure 11: Effect of predictability and efficiency on SAVER.
From: SAVER: gene expression recovery for single-cell RNA sequencing
The SAVER estimate is a weighted average of the normalized observed expression and the predicted expression. The weight is dependent on the predictability of the gene and the cell-specific efficiency. Four scenarios are shown: Predictable (low ϕg) versus unpredictable (high ϕg) gene, in a high or low efficiency experiment. In each of the scatter plots, each point is a gene, and for each gene, the vertical lines connect the normalized observed expression with the gene’s SAVER recovered value, which always lies between the normalized observed expression and the prediction (the 45 degree line).
