Supplementary Figure 3: Extended analysis of 6mA DIP-seq in multiple species.
From: A reassessment of DNA-immunoprecipitation-based genomic profiling
(a) Scatterplot showing correlation between IgG motif similarity for DIP-seq and percentage CA-repeats in the respective genomes for M. musculus n = 11, D. rerio n = 2, X. laevis n = 8, C. elegans n = 1 and E. coli n = 2 biologically independent samples. Correlation calculated as two-tailed Spearman's rho for all samples together (n = 24). Line represents linear correlation and 95% confidence interval. (b) Number and overlap of 6mA enriched regions in X. laevis testes identified using Input or IgG controls shown as Venn diagrams (left) and bar plots (right). (c) Number of reads mapping to Mycoplasma species. Kidney n = 3, mESC n = 2, Brain n = 6 biologically independent samples. Boxplots represent median and first and third quartiles with whiskers extending 1.5 * inter-quartile range.
