Supplementary Figure 2: Characterization of human immune cell reconstitution in BRGST HIS mice. | Nature Methods

Supplementary Figure 2: Characterization of human immune cell reconstitution in BRGST HIS mice.

From: A human immune system mouse model with robust lymph node development

Supplementary Figure 2

(a) Representative pictures indicated LNs in BRGST HIS mice at 10-14 weeks post fetal liver CD34+ cell transplantation from 3 independent experiments with similar results. Scale bar = 2 mm (b) Kinetics of human cell reconstitution in blood of BRGS and BRGST HIS mice (n = 8 mice/group, centre values represent mean, and error bars denote s.e.m.). (c) Representative flow cytometry analysis of human naïve/memory T cell subsets from 12 HIS mice with similar results, identified by expression of CCR7 and CD45RA among hCD45+CD3+CD4+ splenic T cells.

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