Supplementary Figure 6: NMDAR component of postsynaptic potential.
From: All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibition
To isolate the NMDAR component of the PSP, we added 10 μM NBQX and 10 μM picrotoxin to block AMPA and GABAa receptors, respectively, and imaged in a medium containing 0 Mg2+ to remove the voltage-dependent Mg2+ NMDAR block. Ten-trial average (n = 10 neurons; representative data are shown).
