Researchers have carried out the first de novo design of a β-barrel protein and engineered the interior to bind and activate a fluorogenic dye.
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Research papers
Dou, J. et al. De novo design of a fluorescence-activating β-barrel. Nature 561, 485–491 (2018).
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Strack, R. Fluorescent proteins from scratch. Nat Methods 15, 856 (2018). https://doi.org/10.1038/s41592-018-0206-9
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DOI: https://doi.org/10.1038/s41592-018-0206-9